Production method of silybin meglumine tablets

Production method of silybin meglumine tablets

  • CN 101,810,594 A
  • Filed: 03/16/2010
  • Published: 08/25/2010
  • Est. Priority Date: 03/16/2010
  • Status: Active Application
First Claim
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1. the production method of a silybin meglumine tablets is characterized in that, this method comprises the steps:

  • 1) take by weighing silybin meglumine 20%~

    30%, lactose 35%~

    45%, carboxymethylstach sodium 5%~

    10%, silicon dioxide 5%~

    10%, pregelatinized Starch 13%~

    19%, magnesium stearate 0.5%~

    1.5% respectively, all percentage ratios are weight percentage;

    2) be that 80~

    95% ethanol are made soft material with silybin meglumine, lactose, carboxymethylstach sodium, silicon dioxide, the pregelatinized Starch volume content that takes by weighing in the step

         1), then successively 12~

    20 orders granulate, 50 ℃



    80 ℃

    dryings, 14~

    16 order granulate, add magnesium stearate mixing, tabletting, coating, packing again and promptly get described silybin meglumine tablets.

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