Transdermal drug delivery system including the release liner of coating

Transdermal drug delivery system including the release liner of coating

  • CN 101,842,065 B
  • Filed: 08/28/2008
  • Issued: 09/07/2016
  • Est. Priority Date: 09/04/2007
  • Status: Active Grant
First Claim
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1. transdermal delivery device, it includes back sheet, adhesive layer and is coated with the silicon of ultraviolet curingThe release liner of ketone coating,Wherein said adhesive layer comprise the mineral oil of 39 weight %, the polyisobutene (PIB) of 48 weight %, 8The clonidine alkali of weight % and the cataloid (CSD) of 5 weight %,Wherein said adhesive layer contacts with described release liner, andInitial peeling force between wherein said release liner and described adhesive layer is 12 gram inch (g/in),Wherein 25 DEG C and 60% relative humidity under after 1 month, described release liner and described adhesive layerBetween peeling force be 15 gram inch, andWherein 25 DEG C and 60% relative humidity under after 6 months, described release liner and described adhesive layerBetween peeling force be 16 gram inch.

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