High-density lipoprotein-like peptide-phospholipid scaffold (''HPPS'') nanoparticles

High-density lipoprotein-like peptide-phospholipid scaffold (''HPPS'') nanoparticles

  • CN 102,027,019 A
  • Filed: 12/12/2008
  • Published: 04/20/2011
  • Est. Priority Date: 12/12/2007
  • Status: Active Application
First Claim
Patent Images

1. peptide-lipid nanometer support of existing of a non-natural comprises:

  • A) at least a phosphatide;

    B) at least a unsaturated lipids, preferred unsaturated sterol ester, further preferred unsaturated cholesteryl ester, further preferred cholesterol acid ester;

    AndC) at least a peptide, described peptide comprises the aminoacid sequence that can form at least one amphipathic alpha-helix;

    Wherein, make composition a), b) with c) in conjunction with to form peptide-phosphatide nano-bracket.

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