Composition for inhibiting expression of target gene

Composition for inhibiting expression of target gene

  • CN 102,112,136 A
  • Filed: 07/31/2009
  • Published: 06/29/2011
  • Est. Priority Date: 08/01/2008
  • Status: Active Application
First Claim
Patent Images

1. compositions, contain the liposome of having sealed RNA, described RNA contain continuous 15~

  • 30 bases of target gene mRNA sequence (below be designated as sequence X) and with the sequence of the complementary base of described sequence X (below be designated as complementary series X '"'"'), with the ribose of total 1~

    90% for being replaced by modification group on 2 '"'"' of the sugar of the base bonding of sequence X and complementary series X '"'"', described liposome is to arrive the tissue that comprises the expression of target gene position or the liposome of internal organs.

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