Foot and mouth disease virus antigen polypeptide, fusion antigen polypeptide and vaccine

Foot and mouth disease virus antigen polypeptide, fusion antigen polypeptide and vaccine

  • CN 102,180,952 B
  • Filed: 05/10/2011
  • Issued: 01/25/2012
  • Est. Priority Date: 05/10/2011
  • Status: Active Grant
First Claim
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1. a foot-and-mouth disease virus antigen polypeptide is characterized in that, the aminoacid sequence of this antigenic peptide is:

  • (1) Cys Lys Tyr Ala Gly X1 Ser Leu X2Asn Val Arg Gly Asp Leu X3 X4 Leu X5 Gln LysAla Ala Arg X6 Leu Pro Thr Ser Phe Asn Tyr X7 Ala Ile Lys, wherein, X1=Gly or Ala;

    X2=Thr, Leu or Pro, X3=Gln or Leu;

    X4=Val, Glu or Ala, X5=Ala or Asp;

    X6=Pro or Cys, X7=Gly or Cys, and X6 and X7 must have one and can only have one to get Cys;

    Perhaps(2) aminoacid sequence shown in (1) add be no more than obtain behind 10 amino acid have an immunocompetent aminoacid sequence of foot and mouth disease virus.

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