The synthetic method of 2-aryl nitrile thiazole derivative and intermediate thereof

The synthetic method of 2-aryl nitrile thiazole derivative and intermediate thereof

  • CN 102,276,550 B
  • Filed: 06/10/2010
  • Issued: 08/19/2015
  • Est. Priority Date: 06/10/2010
  • Status: Active Grant
First Claim
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1. there is the preparation method as shown in the formula (VI) compound, it is characterized in that, comprise step:

  • C formula (VII) compound that () is following, in halo alkanes reaction solvent, prepares formula (VI) compound with bromine generation electrophilic substitution reaction under Louis acid catalysis,

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