Preparation method of atorvastatin calcium capsule

Preparation method of atorvastatin calcium capsule

  • CN 102,309,467 A
  • Filed: 06/29/2010
  • Published: 01/11/2012
  • Est. Priority Date: 06/29/2010
  • Status: Active Application
First Claim
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1. the method for preparing of an atorvastatin calcium capsule preparation is characterized in that this method for preparing comprises:

  • (1) with amorphous atorvastatin calcium and water-soluble solid dispersible carrier mix homogeneously, the heating make the fusion of solid dispersion carrier, make amorphous atorvastatin calcium be dispersed in fused dispersible carrier after, cooling curing;

    (2) after the mixture cold drying with step (1) acquisition, obtain the granule of mixture;

    (3) granule that step (2) is obtained is inserted capsule with after other pharmaceutic adjuvant mixes.

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