For diagnosing and predicting the biomarker plate of transplant rejection

For diagnosing and predicting the biomarker plate of transplant rejection

  • CN 102,439,172 B
  • Filed: 01/11/2010
  • Issued: 03/01/2017
  • Est. Priority Date: 01/15/2009
  • Status: Active Grant
First Claim
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1. NKTR, MAPK9, DUSP1, PBEF1 and PSEN1 are used for manufacturing the purposes that element is assessed in gene expression, described gene tableReach the acute rejection that assessment element is the subject having accepted allograft for monitoring, the side of described monitoringMethod includes:

  • The expression water of (a) assessment NKTR, MAPK9, DUSP1, PBEF1 and PSEN1 gene in the sample of described subjectPut down to obtain gene expression results;

    WithB () to predict outbreak, the diagnosing acute of acute rejection in described subject using described gene expression resultsRejection and/or sign acute rejection, thus monitor the acute rejection of described subject.

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