Peptide libraries

Peptide libraries

  • CN 102,471,772 A
  • Filed: 08/12/2010
  • Published: 05/23/2012
  • Est. Priority Date: 08/12/2009
  • Status: Active Application
First Claim
Patent Images

1. a conformation that changes first polypeptide ligand or first group of polypeptide ligand is to prepare the method for second polypeptide ligand or second group of polypeptide ligand;

  • Each polypeptide ligand comprises at least two reactive groups being separated to the ring sequence of molecular skeleton by covalently bound;

    Said molecular skeleton and said reactive group form covalent linkage;

    Said method comprises from the structural framework of polypeptide and said first part or first group ligand assembles said second part or second group ligand, adds one of following steps;

    (a);

    change at least one reactive group;

    Or(b);

    the character that changes said molecular skeleton;

    Or(c);

    change the key between at least one reactive group and the said molecular skeleton;

    Or(d);

    (a) and (b) or arbitrary combination (c).

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