As be used for the treatment of cognitive impairment, 1-[2-(2, the 4-dimethylphenylsulfanyl)-phenyl] piperazine of the compound to serotonin reabsorption, 5-HT3 and 5-HT1A activity with combination

As be used for the treatment of cognitive impairment, 1-[2-(2, the 4-dimethylphenylsulfanyl)-phenyl] piperazine of the compound to serotonin reabsorption, 5-HT3 and 5-HT1A activity with combination

  • CN 102,614,179 B
  • Filed: 06/15/2007
  • Issued: 11/25/2015
  • Est. Priority Date: 06/16/2006
  • Status: Active Grant
First Claim
Patent Images

1. the compound l-[2-(2 of crystal form, 4-dimethylphenylsulfanyl)-phenyl] piperazine and pharmaceutically useful salt thereof is for the preparation of the purposes in the medicament of disease therapy, described disease is cognitive impairment, wherein said pharmaceutically useful salt is selected from the hydrobromate with XRPD shown in Fig. 2 or 4, there is the hydrochlorate of XRPD shown in Fig. 7, there is the mesylate of XRPD shown in Fig. 9, there is the fumarate of XRPD shown in Figure 10, there is the maleate of XRPD shown in Figure 11, there is the mesotartaric acid salt of XRPD shown in Figure 12, there is L-(+)-tartrate of XRPD shown in Figure 13, there is D-(-)-tartrate of XRPD shown in Figure 14, there is the sulfate of XRPD shown in Figure 15, there is the phosphate of XRPD shown in Figure 16 or there is the nitrate of XRPD shown in Figure 17.

View all claims
    ×
    ×

    Thank you for your feedback

    ×
    ×