Anti-glypican 3 antibody

Anti-glypican 3 antibody

  • CN 102,702,353 A
  • Filed: 07/08/2005
  • Published: 10/03/2012
  • Est. Priority Date: 07/09/2004
  • Status: Active Application
First Claim
Patent Images

1. comprise having as follows (1)-(12) each CDRs 1,2 and antibody of 3 variable region of heavy chain:

  • (1) contain the CDR1 of aminoacid sequence shown in the SEQ ID NO;

    123, contain the CDR2 of aminoacid sequence shown in the SEQ ID NO;

    124, and the CDR3 that contains aminoacid sequence shown in the SEQ ID NO;

    125;

    (2) contain the CDR1 of aminoacid sequence shown in the SEQ ID NO;

    109, contain the CDR2 of aminoacid sequence shown in the SEQ ID NO;

    110, and the CDR3 that contains aminoacid sequence shown in the SEQ ID NO;

    111;

    (3) contain the CDR1 of aminoacid sequence shown in the SEQ ID NO;

    106, contain the CDR2 of aminoacid sequence shown in the SEQ ID NO;

    107, and the CDR3 that contains aminoacid sequence shown in the SEQ ID NO;

    108;

    (4) contain the CDR1 of aminoacid sequence shown in the SEQ ID NO;

    132, contain the CDR2 of aminoacid sequence shown in the SEQ ID NO;

    133, and the CDR3 that contains aminoacid sequence shown in the SEQ ID NO;

    134;

    (5) contain the CDR1 of aminoacid sequence shown in the SEQ ID NO;

    106, contain the CDR2 of aminoacid sequence shown in the SEQ ID NO;

    135, and the CDR3 that contains aminoacid sequence shown in the SEQ ID NO;

    136;

    (6) contain the CDR1 of aminoacid sequence shown in the SEQ ID NO;

    126, contain the CDR2 of aminoacid sequence shown in the SEQ ID NO;

    127, and the CDR3 that contains aminoacid sequence shown in the SEQ ID NO;

    128;

    (7) contain the CDR1 of aminoacid sequence shown in the SEQ ID NO;

    129, contain the CDR2 of aminoacid sequence shown in the SEQ ID NO;

    130, and the CDR3 that contains aminoacid sequence shown in the SEQ ID NO;

    131;

    (8) contain the CDR1 of aminoacid sequence shown in the SEQ ID NO;

    103, contain the CDR2 of aminoacid sequence shown in the SEQ ID NO;

    104, and the CDR3 that contains aminoacid sequence shown in the SEQ ID NO;

    105;

    (9) contain the CDR1 of aminoacid sequence shown in the SEQ ID NO;

    118, contain the CDR2 of aminoacid sequence shown in the SEQ ID NO;

    121, and the CDR3 that contains aminoacid sequence shown in the SEQ ID NO;

    122;

    (10) contain the CDR1 of aminoacid sequence shown in the SEQ ID NO;

    115, contain the CDR2 of aminoacid sequence shown in the SEQ ID NO;

    116, and the CDR3 that contains aminoacid sequence shown in the SEQ ID NO;

    117;

    (11) contain the CDR1 of aminoacid sequence shown in the SEQ ID NO;

    112, contain the CDR2 of aminoacid sequence shown in the SEQ ID NO;

    113, and the CDR3 that contains aminoacid sequence shown in the SEQ ID NO;

    114;

    Or(12) contain the CDR1 of aminoacid sequence shown in the SEQ ID NO;

    118, contain the CDR2 of aminoacid sequence shown in the SEQ ID NO;

    119, and the CDR3 that contains aminoacid sequence shown in the SEQ ID NO;

    120.

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