Treatment of tumor protein 63 (p63) related diseases by inhibition of natural antisense transcript to p63

Treatment of tumor protein 63 (p63) related diseases by inhibition of natural antisense transcript to p63

  • CN 102,770,540 A
  • Filed: 12/29/2010
  • Published: 11/07/2012
  • Est. Priority Date: 12/29/2009
  • Status: Active Grant
First Claim
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1. the function of oncoprotein 63 (p63) polynucleotide and/or the method for expression in the body or in the external adjusting patient cell or tissue, said method comprises:

  • With said cell or tissue and length is that at least a antisense oligonucleotide of 5 to 30 Nucleotide contacts, and the reverse complementary sequence of the polynucleotide of 5 to 30 continuous nucleotides in wherein said at least a oligonucleotide and the Nucleotide 1 to 288 that comprises SEQ ID NO;

    2 has at least 50% sequence identity;

    Thereby the function and/or the expression of oncoprotein 63 (p63) polynucleotide in the interior or external adjusting of the body patient cell or tissue.

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