Targeted heterologous antigen presentation on calicivirus virus-like particles

Targeted heterologous antigen presentation on calicivirus virus-like particles

  • CN 102,791,286 A
  • Filed: 01/21/2011
  • Published: 11/21/2012
  • Est. Priority Date: 01/21/2010
  • Status: Active Grant
First Claim
Patent Images

1. chimeric protein;

  • It comprises cupular virus capsid protein and at least a heterologous antigen or its fragment with P2 territory;

    Wherein said at least a heterologous antigen or its fragment are inserted in the said P2 territory of said capsid protein, and wherein said chimeric protein forms virus-like particle can in host cell, express the time.

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