Epidemic encephalitis B/dengue chimeric virus with epidemic encephalitis B virus attenuated strain as gene framework and application of epidemic encephalitis B/dengue chimeric virus

Epidemic encephalitis B/dengue chimeric virus with epidemic encephalitis B virus attenuated strain as gene framework and application of epidemic encephalitis B/dengue chimeric virus

  • CN 102,796,749 B
  • Filed: 05/27/2011
  • Issued: 05/24/2017
  • Est. Priority Date: 05/27/2011
  • Status: Active Grant
First Claim
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1. a kind of DNA molecular, is to replace the encoding gene of the a-protein in the corresponding cDNA of the geneome RNA of encephalitis B virusFor the recombinant DNA that the encoding gene of PROTEIN B is obtained;

  • The a-protein is the protein that the amino acid sequence shown in sequence in sequence table 1 is constituted;

    The PROTEIN B is the protein that the amino acid sequence shown in sequence in sequence table 2 is constituted;

    The corresponding cDNA sequence of geneome RNA of the encephalitis B virus is as shown in sequence 6 in sequence table.

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