Treatment of pancreatic developmental gene related diseases by inhibition of natural antisense transcript to a pancreatic developmental gene

Treatment of pancreatic developmental gene related diseases by inhibition of natural antisense transcript to a pancreatic developmental gene

  • CN 102,822,342 B
  • Filed: 01/06/2011
  • Issued: 05/10/2017
  • Est. Priority Date: 01/06/2010
  • Status: Active Grant
First Claim
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1. at least one ASON of the natural antisense transcript of targeted pancreatic development gene polynucleotides is preparing bodyThe interior or external use raised in Patient cells or tissue in the function of Pancreatic Developmental gene polynucleotides and/or the medicine of expressionOn the way, the length of the ASON is 10 to 30 nucleotides, and the sequence of the natural antisense transcript is selected from SEQ IDNO:

  • 6 to 12, and the sequence of wherein described at least one ASON is selected from SEQ ID NO;

    14、

    18、

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    22-23、

    25-31,34,40-41 and 43-44.

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