With reference to human antigen's associated proteins of β KLOTHO, FGF receptor and its compound

With reference to human antigen's associated proteins of β KLOTHO, FGF receptor and its compound

  • CN 102,858,802 B
  • Filed: 12/03/2010
  • Issued: 02/02/2018
  • Est. Priority Date: 12/07/2009
  • Status: Active Grant
First Claim
Patent Images

1. a kind of antibody of separation or its fragment, it induces the signal transduction of FGF21 mediations and includes following CDR:

  • a) CDRH1:

    SEQ ID NO;

    122;

    b) CDRH2:

    SEQ ID NO;

    133;

    c) CDRH3:

    SEQ ID NO;

    148;

    d) CDRL1:

    SEQ ID NO;

    166;

    e) CDRL2:

    SEQ ID NO;

    176;

    Withf) CDRL3:

    SEQ ID NO;

    188.

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