Treatment of colony-stimulating factor 3 (CSF3) related diseases by inhibition of natural antisense transcript to CSF3

Treatment of colony-stimulating factor 3 (CSF3) related diseases by inhibition of natural antisense transcript to CSF3

  • CN 102,869,777 A
  • Filed: 04/01/2011
  • Published: 01/09/2013
  • Est. Priority Date: 04/02/2010
  • Status: Active Grant
First Claim
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1. the function of G CFS 3 (CSF3) polynucleotide and/or the method for expression in the body or in the external adjusting patient cell or tissue, described method comprises:

  • Be that at least a antisense oligonucleotide of 5 to 30 Nucleotide contacts with described cell or tissue and length, the reverse complementary sequence of the polynucleotide of 5 to 30 continuous nucleotides in wherein said at least a oligonucleotide and the Nucleotide 1 to 742 that comprises SEQ ID NO;

    2 has at least 50% sequence identity;

    Thereby function and/or the expression of G CFS 3 (CSF3) polynucleotide in the interior or external adjusting of the body patient cell or tissue.

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