Optimize system and method for testing with the insulin for exiting standard through overregulating for considering the system noise associated with biological marker

Optimize system and method for testing with the insulin for exiting standard through overregulating for considering the system noise associated with biological marker

  • CN 102,946,804 B
  • Filed: 06/14/2011
  • Issued: 09/22/2017
  • Est. Priority Date: 06/18/2010
  • Status: Active Grant
First Claim
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1. a kind of system for being configured to instruct diabetic by test plan, including:

  • The processor of memory is coupled to, wherein the memory includes collecting code;

    AndSoftware with instruction, causes the processor when the instruction is by the computing device:

    Indicate the diabetic via user interface and collected according to the collection code one of biomarker data orMultiple sampling set, are adopted wherein set of each sampling is included in record in the collection period in one or more of described memorySample example, and each sampling instance includes one or more biological marker readings;

    AndBy the processor or other processors come the sampling set for biomarker data it is total calculate probability-distribution function,Dangerous function, risk function and risk numerical value, wherein,The probability-distribution function for the probability distribution for being similar to the biomarker data is calculated,Dangerous function be it is a kind of for it is described sampling set in instruction compared with high concurrent disease risk biological marker reading produce compared withThe function of high-risk numerical value, wherein passing through equationTo define dangerous functionH(B), whereinBIt is the biological marker reading in sampling set,Hhypo(B)It is the dangerous function associated with hypoglycemic event,Hhyper(B)Be withThe associated dangerous function of hyperglycemic,Risk function is the product of probability-distribution function and dangerous function, andPass through the integration of risk functionIt is probability to come calculation risk numerical value J, wherein p (B)Distribution;

    Indicating the diabetic makes risk numerical minimization by adjusting the therapy of patient, or if at least oneThe risk numerical value of individual sampling set is minimized to optimal risk level and then exited,Wherein described collection code is that code is collected in structuring.

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