Cross-species-specific psmaxcd3 bispecific single chain antibody

Cross-species-specific psmaxcd3 bispecific single chain antibody

  • CN 103,025,759 A
  • Filed: 04/01/2011
  • Published: 04/03/2013
  • Est. Priority Date: 04/01/2010
  • Status: Active Application
First Claim
Patent Images

1. bispecific single-chain antibody molecule, its comprise first in conjunction with territory and second in conjunction with the territory, described first is the AI site and can be bonded to human and white temples marmoset in conjunction with the territory, the epi-position of suede top Chinese tamarisk monkey or Squirrel monkey CD3 ε

  • (epsilon) chain, wherein said epi-position is included in SEQ ID NO.2, SEQ ID NO.4, the part of the aminoacid sequence among SEQ ID NO.6 and the SEQ ID NO.8 and comprise at least aminoacid sequence Gln-Asp-Gly-Asn-Glu(QDGNE), described second can be bonded to Prostato-specific membrane antigen (PSMA) in conjunction with the territory.

View all claims
    ×
    ×

    Thank you for your feedback

    ×
    ×