Liquid formulations of rupatadine fumarate

Liquid formulations of rupatadine fumarate

  • CN 103,108,635 B
  • Filed: 06/30/2011
  • Issued: 10/15/2014
  • Est. Priority Date: 06/30/2010
  • Status: Active Grant
First Claim
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1. without a cyclodextrin aqueous liquid pharmaceutical compositions, it comprises:

  • -Rupatadine fumarate, its concentration is the Rupatadine fumarate of 0.5 to 1.5g (Rupatadine)/L;

    -one or more cosolvent, described cosolvent is to comprise the cosolvent that one or more select the group that free ethanol, isopropyl alcohol, propylene glycol, glycerol, Liquid Macrogol, PEG400, dimethyl acetylamide and ketopyrrolidine form;

    The total amount of described cosolvent is 5 to 50% of said preparation;

    And-one or more select the pH adjusting agent of the group that free buffer agent and alkali forms,Wherein the pH of said composition is between 4 and 6.5, andWherein said composition is solution.

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