Desloratadine nanoemulsion and preparation method thereof

Desloratadine nanoemulsion and preparation method thereof

  • CN 103,432,075 A
  • Filed: 09/17/2013
  • Published: 12/11/2013
  • Est. Priority Date: 09/17/2013
  • Status: Active Application
First Claim
Patent Images

1. a Desloratadine nano-emulsion, it is characterized in that, the size droplet diameter of this nano-emulsion is between 10~

  • 100 nm, raw material by following weight percentage ratio is made;

    Desloratadine 0.01 ﹪



    0.10 ﹪

    , ethyl acetate 6.00 ﹪



    36.00 ﹪

    , surfactant 14.00 ﹪



    36.00 ﹪

    , cosurfactant 10.00 ﹪



    20.00 ﹪ and

    distilled water 7.90%~

    60.98% form, and total component is 100 ﹪

    ;

    Oils and fats recited above is ethyl acetate;

    Surfactant is tween 80 or castor oil polyoxyethylene ether;

    Cosurfactant has ethanol, 1,2-PD, glycerol and n-butyl alcohol.

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