Method for manufacturing composition comprising local anesthetic, heparinoid, and buffer

Method for manufacturing composition comprising local anesthetic, heparinoid, and buffer

  • CN 103,747,790 A
  • Filed: 01/05/2012
  • Published: 04/23/2014
  • Est. Priority Date: 01/06/2011
  • Status: Active Application
First Claim
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1. preparation can be used for by compositions being instilled into the method for the treatment of the compositions of lower urinary tract disorders in bladder, and described compositions comprises the mixture that contains heparinoid, local anesthetic and buffer agent, and described method comprises the following steps:

  • (a) provide the heparinoid of solid form or liquid form;

    (b) provide the local anesthetic of solid form or liquid form;

    (c) heparinoid to described solid form or liquid form adds liquid buffer;

    (d) mixture to described liquid buffer and heparinoid adds described local anesthetic;

    And(e) if needed, adjust the pH of the mixture of described liquid buffer, local anesthetic and heparinoid, to obtain approximately 6.7 to approximately 8.3 pH, there is no the precipitation of described local anesthetic.

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