Methods and compositions for neuroprotection

Methods and compositions for neuroprotection

  • CN 103,917,647 B
  • Filed: 11/01/2012
  • Issued: 07/10/2020
  • Est. Priority Date: 11/03/2011
  • Status: Active Grant
First Claim
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1. Use of a double stranded rna (dsrna) compound that down-regulates expression of a CASP2 gene encoding an mRNA having a sequence set forth in any one of SEQ ID NOs 1-3 in the manufacture of a medicament for neuroprotection of neurons comprised in a spiral ganglion and/or a vestibular ganglion in an ear of a subject in need thereof, wherein the subject is suffering from or susceptible to meniere'"'"'s disease.

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