Efficient synthesis method of antioxidant 168

Efficient synthesis method of antioxidant 168

  • CN 104,370,956 A
  • Filed: 10/24/2014
  • Published: 02/25/2015
  • Est. Priority Date: 10/24/2014
  • Status: Active Application
First Claim
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1. a high-efficiency synthesis method for irgasfos 168, is characterized in that, comprises following steps:

  • 1., 2,4-DTBP and catalyzer are added in container, then slowly add the mixed solution of dimethylbenzene and phosphorus trichloride, be warming up to 50 ~ 60 DEG C, reaction 2 ~ 5h;

    Described catalyzer is the mixture of DMAP and triethylamine;

    2., by step 1. in the reaction solution that obtains be warming up to 130 ~ 160 DEG C, reaction 1.5 ~ 5h, underpressure distillation goes out hydrogenchloride and dimethylbenzene;

    3., by step 2. in reaction solution after underpressure distillation be cooled to 90 DEG C, add Virahol, after stirring 0.5 ~ 1.5h, be cooled to room temperature, suction filtration, be drying to obtain irgasfos 168.

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