Toxicity management for anti-tumor activity of CARS

Toxicity management for anti-tumor activity of CARS

  • CN 104,427,997 A
  • Filed: 07/12/2013
  • Published: 03/18/2015
  • Est. Priority Date: 07/13/2012
  • Status: Active Application
First Claim
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1. treatment suffer from associate with the expression of the raising of tumor antigen disease, imbalance or disease the method for patient, the method comprises and gives its patient'"'"'s First Line in need treatment and second line treatment, wherein this First Line treatment comprise give this patient effective amounts genetic modification to express the cell of CAR, wherein this CAR comprises antigen binding domain, membrane spaning domain and Cellular Signaling Transduction Mediated territory.

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