Inhalable dry powders

Inhalable dry powders

  • CN 104,487,075 A
  • Filed: 02/28/2013
  • Published: 04/01/2015
  • Est. Priority Date: 02/29/2012
  • Status: Active Application
First Claim
Patent Images

1. a dry powder doses inhaler, described dry powder doses inhaler comprises container, be placed with in the above-described container and can suck dry powder doses, the wherein said dry powder doses that sucks forms by sucking dried particle, describedly suck the volume-median geometric diameter (VMGD) that dried particle has about 10 microns or less, at least about the tap density of 0.45g/ cubic centimetre, and comprise and a) be selected from monovalent metal cation salt, one or more metal cation salt of divalent metal salt and its combination, and b) one or more therapeutic agents, described one or more therapeutic agents account for the gross mass held in described container about 25% or more,In described container, the described gross mass of dry powder doses is about 25 milligrams or more, and described container has the volume being less than 400 microlitres, and the volume of described container is full of 50% or more by described dry powder doses;

  • AndWhen activating described dry powder doses inhaler in the Andersen Cascade Impactor run under the pressure drop at about 4kPa, produce the particulate dosage (FPD (<

    4.4)) being less than 4.4 microns of about 25 milligrams or more.

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