Week-acting transdermal pramipexole patch and preparation method thereof

Week-acting transdermal pramipexole patch and preparation method thereof

  • CN 104,510,725 A
  • Filed: 01/22/2015
  • Published: 04/15/2015
  • Est. Priority Date: 01/22/2015
  • Status: Active Application
First Claim
Patent Images

1. the weekly-acting percutaneous patch of pramipexole is by medicated layer, adherent layer with formed by lining, wherein drug-carrying polymer layer consist of medicine 1 part;

  • Medicine carrying material 10 ~ 300 parts;

    Penetrating agent 7 ~ 120 parts;

    Plasticizer 7 ~ 120 parts;

    Stabilizing agent 7 ~ 120 parts;

    Medicated layer is two-layer, and the medicine being wherein close to backing layer accounts for the 45%-90% of medicine total amount, is 1 point of gauge with two-layer contained medicine total amount, in this layer, the weight of polymer is 6-140 part, the weight of penetrating agent is 3-50, and the weight of plasticizer is 4-60 part, and the weight of stabilizing agent is 3-50 part;

    The medicine of internal layer accounts for the 10%-55% of medicine total amount, and be 1 point of gauge with two-layer contained medicine total amount, in this layer, the weight of polymer is 4-160 part, and the weight of penetrating agent is 4-70, and the weight of plasticizer is 3-60 part, and the weight of stabilizing agent is 4-70 part.

View all claims
    ×
    ×

    Thank you for your feedback

    ×
    ×