Prolactin antagonist receptor antibody preparation

Prolactin antagonist receptor antibody preparation

  • CN 104,736,175 B
  • Filed: 08/28/2013
  • Issued: 11/01/2019
  • Est. Priority Date: 08/31/2012
  • Status: Active Grant
First Claim
Patent Images

1. a kind of anti-PRLR antibody preparation, it includes:

  • A.10mM histidine;

    B.75ppm polysorbate80 and 10mM methionine or 80ppm polysorbate80 and 5mM methionine;

    C.234mM sucrose;

    D.30mM arginine;

    AndE.60mg/ml anti-PRLR antibody;

    Wherein the pH range of the anti-PRLR antibody preparation is pH5.0 to pH6.5;

    Wherein the anti-PRLR antibody preparation is not in addition to including inorganic salts other than buffering the organic salt or inorganic salts of the preparation;

    Wherein the anti-PRLR antibody is human IgG2'"'"'s monoclonal antibody;

    Wherein human IgG2'"'"'s monoclonal antibody includes the sequence of light chain of SEQ ID NO;

    1 and the sequence of heavy chain of SEQ ID NO;

    7.

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