Microfluid cell sorting system driven by external piezoelectric ceramic

Microfluid cell sorting system driven by external piezoelectric ceramic

  • CN 104,830,664 A
  • Filed: 05/07/2015
  • Published: 08/12/2015
  • Est. Priority Date: 05/07/2015
  • Status: Active Grant
First Claim
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1. based on a Microfluidic cell separation system for external Piezoelectric Ceramic, it is characterized in that:

  • comprise a microfluid sorting chip, a sample introduction module, an optical detecting module, a real-time signal control module, a Piezoelectric Ceramic module and more than one piezoelectric ceramics;

    Be packaged with the metal clips driven as sorting in described microfluid sorting chip, described piezoelectric ceramics is arranged on outside described metal clips;

    The import of described sample introduction module connects a gas cylinder, the outlet of described sample introduction module connects the import of described microfluid sorting chip, cell sample and oil phase sheath fluid are pressed in the microchannel of described microfluid sorting chip by controlling gaseous tension by described sample introduction module, make described oil phase sheath fluid stream cell sample stream is strapped in the testing pipes central authorities of described microfluid sorting chip, and ensure individual cells successively by the surveyed area of described microfluid sorting chip;

    Described optical detecting module is for each cell flowing through the testing pipes of described microfluid sorting chip that throws light on, activated cell produces fluorescence and scattered light, complete the collection of fluorescence and scattered light, and fluorescence detection obtained and scattered light signal are sent to described real-time signal control module;

    Scattered light and fluorescent signal are converted into electrical signal and carry out nursing one'"'"'s health and quantification treatment by described real-time signal control module, and result and user'"'"'s settings are carried out Logic judgment, if meet user to set sorting requirement, send triggering signal to described Piezoelectric Ceramic module;

    Triggering signal is converted to the high voltage signal driving described piezoelectric ceramics by described Piezoelectric Ceramic module, make described piezoelectric ceramics produce mechanical shift and by extruding or discharging described metal clips, target cell be separated to different sorting outlets, realizing cell sorting.

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