Compositions for treating centrally mediated nausea and vomiting

Compositions for treating centrally mediated nausea and vomiting

  • CN 104,856,999 A
  • Filed: 11/18/2010
  • Published: 08/26/2015
  • Est. Priority Date: 11/18/2009
  • Status: Active Application
First Claim
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1. contain the peroral dosage form of palonosetron and Netupitant or its officinal salt, it comprises:

  • A) shell;

    B) one or more Netupitant unit be encapsulated in described shell, each unit comprises instituteState Netupitant or its officinal salt and one or more pharmaceutically acceptable excipient;

    AndC) one or more palonosetron unit be encapsulated in described shell, each unit comprisesDescribed palonosetron and one or more pharmaceutically acceptable excipient;

    Wherein said dosage form comprises (3S)-3-[(3aS)-1-oxo-2,3,3a, 4,5,6-six hydrogen-1H-benzo [de] isoquinolin-2-yl] pungent-1-acid esters of-1-azabicyclo [2.2.2] of the amount being no more than 3 % by weight.

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