Novel Microbial Succinic Acid Producers And Purification Of Succinic Acid

Novel Microbial Succinic Acid Producers And Purification Of Succinic Acid

  • CN 104,877,935 A
  • Filed: 02/12/2010
  • Published: 09/02/2015
  • Est. Priority Date: 02/16/2009
  • Status: Active Application
First Claim
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1. glycerine can be utilized to produce the bacterial isolates of succsinic acid as carbon source through fermentation, wherein said bacterial strain is through genetic modification, endogenous pyruvic acid-the formic acid making it comprise imbalance-lyase is active, wherein said pyruvic acid-formic acid-lyase activity reduces or closes, described bacterial strain is derived from the microorganism being selected from Pasteurellaceae (Pasteurellaceae) microorganism, the transformation of glycerol of at least 25g/L is at least 25.1g/L succsinic acid by it, yield coefficient YP/S is at least 1.01g/g, wherein at least one carbon source is converted into succsinic acid, its space-time yield is at least 2.2g/ (L h) succsinic acid, described carbon source is selected from sucrose, maltose, D-Fructose, D-Glucose, D-wood sugar, L-arabinose, D-semi-lactosi, lactose, D-MANNOSE and/or glycerine.

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