Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism

Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism

  • CN 104,911,136 A
  • Filed: 03/22/2010
  • Published: 09/16/2015
  • Est. Priority Date: 08/28/2009
  • Status: Active Application
First Claim
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1. a bacterial strain for Escherichia, it has the O-acetylhomoserine output of raising, and wherein the activity of following enzyme is enhanced in the Escherichia bacterial strain producing O-acetylhomoserine:

  • (a) homoserine acetyltransferase, E.C. 2.7.2.4. and homoserine dehydrogenase;

    WithB () at least one is selected from the enzyme of phosphoric acid enol pyruvic acid carboxylase, aspartic transaminase and aspartate-semialdehyde dehydrogenase,And wherein the metB gene of encoding cystathionine γ

    synthase is deleted or lacked to being characterized as further of Escherichia bacterial strain.

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