Film-forming pharmaceutical composition for wound healing and method for preparing the same

Film-forming pharmaceutical composition for wound healing and method for preparing the same

  • CN 104,994,843 B
  • Filed: 02/11/2014
  • Issued: 07/07/2020
  • Est. Priority Date: 02/13/2013
  • Status: Active Grant
First Claim
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1. A pharmaceutical composition for wound healing, comprising:

  • (a) a pharmaceutically active substance;

    (b) chitosan or a salt thereof as a film-forming substance; and

    (c) a solvent for dissolving the chitosan, the solvent comprising water and at least one lower alcohol having 1 to 4 carbon atoms, wherein;

    containing the film-forming material in an amount of 0.4 to 20% by weight relative to the total weight of the composition,the composition further comprises a cream based component and the weight ratio of the film forming material to the cream based component is 1;

    50 or greater;

    the paste-based component is selected from the group consisting of;

    isopropyl palmitate, cetyl palmitate, paraffin, glyceryl trioctoate, soybean oil, sesame oil, olive oil, liver oil, oleic acid, octyldodecanol stearate, octyldodecanol myristate, silicone compounds such as dimethicone or simethicone, stearyl alcohol, stearyl glycyrrhetinate, polyoxyethylene stearate, squalane, cetostearyl alcohol, sorbitan sesquioleate, petrolatum, white beeswax, myristyl alcohol, isopropyl myristate, sorbitan monooleate, sorbitan monostearate, glyceryl monostearate, lecithin, hydrogenated castor oil, caprylic-capric triglyceride, lanolin, oleoyl macrogol and mixtures thereof; and

    isThe pharmaceutical composition forms a film upon application to the skin and evaporation or volatilization of the solvent.

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