Silica nanoparticles and their use for vaccination

Silica nanoparticles and their use for vaccination

  • CN 105,126,115 B
  • Filed: 07/13/2009
  • Issued: 11/27/2020
  • Est. Priority Date: 07/15/2008
  • Status: Active Grant
First Claim
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1. Use of a dispersion for the preparation of a vaccine for parenteral administration for immunotherapy, comprising:

  • (i) monodisperse and non-aggregated nanoparticles comprising a silica matrix, wherein the particles have a particle size between 5 and 50nm, wherein the silica matrix has at least one surface functional group on which at least one antigen is immobilized, and (ii) a solvent.

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