Contain α, the preparation method of the powder of alpha trehalose dihydrochloride dihydrate crystal

Contain α, the preparation method of the powder of alpha trehalose dihydrochloride dihydrate crystal

  • CN 105,218,597 B
  • Filed: 09/12/2012
  • Issued: 10/10/2017
  • Est. Priority Date: 09/21/2011
  • Status: Active Grant
First Claim
Patent Images

1. the powder containing a, a-trehalose dihydrochloride dihydrate crystal of the feature with following (1) to (3):

  • (1) more than the 99.2 mass % converted based on anhydride and below 99.7 mass % a, a-trehalose are contained;

    (2) crystallinity of a, a-trehalose dihydrochloride dihydrate crystal calculated based on x-ray diffractogram of powder spectrum is more than 91.0%And less than 96.8%;

    With(3) particle diameter is more than 53 μ

    m and the particle less than 425 μ

    m accounts for all more than the 70 mass % of powder, and particle diameter is more than 53 μ

    mAnd the particle less than 300 μ

    m accounts for all more than the 50 mass % of powder.

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