Blood flow control system and method for in vivo imaging and other applications

Blood flow control system and method for in vivo imaging and other applications

  • CN 105,682,552 B
  • Filed: 10/14/2014
  • Issued: 08/10/2021
  • Est. Priority Date: 10/18/2013
  • Status: Active Grant
First Claim
Patent Images

1. A system for in vivo acquisition of images of the interior of a human body (20) or images based on quantification of blood flow conditions, comprising-an imaging system (21), and-a respiratory resistance device (10) applied to the respiratory system of the body (20), wherein the respiratory resistance device (10) comprises:

  • a body (11) having one or more openings (121,

         122) which, in use, are connected with the respiratory system of the human body (20);

    an internal volume that encloses an internal volume or that has one or more restricted orifices (111), the one or more restricted orifices (111) partially obstructing the flow of air into or out of the respiratory system of the body (20) during an inhalation phase or an exhalation phase, respectively; and

    a control signal generator (14) for generating a control signal indicative of a deviation from a desired breathing state or from a preset pressure value or range of pressure values,wherein-in the human body (20), a substance selected from a contrast fluid, a dye or a drug flows in the blood circulation,-positioning the human body (20) with respect to the imaging system (21), and-performing an image acquisition step during an inspiration phase during which the human body (20) provides suction against the resistance provided by the respiratory resistance device (10) and/or during an expiration phase during which the human body (20) provides expiration against the resistance provided by the respiratory resistance device (10), thereby increasing the quality of the image obtained by the imaging system (21) in the image acquisition step by controlling the distribution of the substance in the blood circulation through the selection of the breathing state by means of a controlled interaction between the respiratory system of the human body (20) and the respiratory resistance device (10).

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