Brain electrophysiological signal recording device and method for transcranial ultrasonic nerve stimulation

Brain electrophysiological signal recording device and method for transcranial ultrasonic nerve stimulation

  • CN 106,037,723 B
  • Filed: 05/17/2016
  • Issued: 11/10/2020
  • Est. Priority Date: 05/17/2016
  • Status: Active Grant
First Claim
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1. An apparatus for recording electrophysiological signals for the brain for transcranial ultrasound nerve stimulation, comprising:

  • a computer (305), a data collector (304), a preamplifier (303), a recording electrode (310) and an ultrasonic transducer (401);

    wherein the content of the first and second substances,the recording electrode (310) is used for recording the brain electrophysiological signals and transmitting the electrophysiological signals to the preamplifier (303);

    the preamplifier (303) is used for receiving the electrophysiological signals recorded by the recording electrode (310), amplifying the electrophysiological signals and transmitting the amplified electrophysiological signals to the data collector (304);

    the data acquisition unit (304) is used for receiving and acquiring the electrophysiological signals amplified by the preamplifier (303), converting the electrophysiological signals into digital signals and inputting the digital signals into the computer (305);

    the computer (305) is used for recording and subsequent data processing and displaying of the electrophysiological signals;

    the ultrasonic transducer (401) is used for generating ultrasonic waves so as to realize a stimulation function on target nerve tissues;

    the lower end of the recording electrode (310) extends into an electrode insertion point (309), and the rest part of the recording electrode (310) is bent at the electrode insertion point (309) and is tightly attached to the surface of the test object;

    the ultrasonic transducer (401) is arranged above an electrode insertion site (309) and a coupling medium (402) is added on the contact surface of the ultrasonic transducer (401) and the experimental object;

    the recording electrode (310) bending position is determined by the following method;

    inserting a recording electrode (310) into a target brain region of an experimental subject along a small hole, and finely adjusting the position of the recording electrode (310) up and down until a peak potential signal is obviously recorded;

    fixing the position of the recording electrode (310) with the electrode insertion site (309);

    the recording electrode (310) is bent at an electrode insertion site (309).

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