(S) (+)-2-oxyethyl group-4-[N-[1-(2-piperidino-phenyl)-3-methyl isophthalic acid-butyl] amino carbonyl methyl] phenylformic acid, contain pharmaceutical composition of this compound and preparation method thereof

(S) (+)-2-oxyethyl group-4-[N-[1-(2-piperidino-phenyl)-3-methyl isophthalic acid-butyl] amino carbonyl methyl] phenylformic acid, contain pharmaceutical composition of this compound and preparation method thereof

  • CN 1,068,820 A
  • Filed: 07/22/1991
  • Published: 02/10/1993
  • Est. Priority Date: 04/02/1998
  • Status: Active Grant
First Claim
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1. A process for the preparation of (S) (+) -2-ethoxy-4- [ N- [1- (2-piperidino-phenyl) -3-methyl-1-butyl]aminocarbonylmethyl]benzoic acid and salts thereof with inorganic or organic acids or bases, characterized in that:

  • a) reacting (S) -amines of the formula (I)(Ⅰ

    )With a carboxylic acid of the general formula (II);

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