Lentiviral vectors for preparation of immunotherapeutical compositions

Lentiviral vectors for preparation of immunotherapeutical compositions

  • CN 1,379,820 A
  • Filed: 10/10/2000
  • Published: 11/13/2002
  • Est. Priority Date: 10/11/1999
  • Status: Active Grant
First Claim
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1. the immunogenic composition that comprises recombinant vectors, this carrier is characterised in that it contains the polynucleotide that comprise initiator, cis acting center (cPPT) and cis acting terminator (CTS), these zones are retrovirus or retrovirus sample origin, in addition said carrier also comprises the reverse transcription of definite nucleotide sequence (transgenosis or interested sequence) and retrovirus or retrovirus sample origin, the conditioning signal of expression and encapsidate, wherein this immunogenic composition can be induced or stimulate at one or several cell-mediated reaction by the epi-position of the transgenic sequence coding that exists in the carrier, for example CTL (cytotoxic T lymphocyte) reaction or CD4 reaction.

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