Oligomer array with PNA and/or DNA oligomers on surface

Oligomer array with PNA and/or DNA oligomers on surface

  • CN 1,413,263 B
  • Filed: 11/24/2000
  • Issued: 07/04/2012
  • Est. Priority Date: 11/25/1999
  • Status: Active Grant
First Claim
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1. the oligomer array that has PNAG3 and/or DNA-oligomer on the surface comprises each oligomer by 6-20 monomer or nuclear based composition,(a) wherein, said monomer or nuclear base comprise general formula D DCGDD at least, or general formula D DTGDD, or general formula HHCGHH, or a kind of sequence of general formula HHCAHH,(b) wherein, at least 75% oligonucleotide comprises general formula D DCGDD, or general formula D DTGDD, or general formula HHCGHH, or a kind of sequence of general formula HHCAHH,(c) wherein, said oligomer array comprises at least 100 different oligomers,(d) wherein, on behalf of a kind of base and the D in VITAMIN B4 A, cytosine(Cyt) C or the thymus pyrimidine T base, H represent a kind of base in VITAMIN B4 A, guanine G or the thymus pyrimidine T base,(e) wherein, oligomer position from the teeth outwards is relevant with the sequence of oligomer.

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