A method of production of LgG

A method of production of LgG

  • CN 1,419,566 A
  • Filed: 03/29/2001
  • Published: 05/21/2003
  • Est. Priority Date: 03/30/2000
  • Status: Abandoned Application
First Claim
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1. method of producing medical IgG by blood plasma, this method comprises at least:

  • (i '"'"') remove albumin to form the IgG part, (ii '"'"') is by being adsorbed onto IgG on the cationite, regather adsorbed IgG part, IgG in the IgG part that purifying is obtained by step (i '"'"'), (iii '"'"') partly carries out inactivation of virus to the IgG IgG partly that comes free step (ii '"'"') collection, the method is characterized in that;

    (I) concentrate the IgG part that is obtained by step (i '"'"'),(II) pH to 4 ±

    0.1 of the IgG part that discharges from cationite in the regulating step (ii '"'"') preferably all keeps pH to be lower than 6.0 in the aftermentioned step;

    With(III) carry out inactivation of virus (step I ii '"'"') with chemical reagent, under 30 ℃

    ±

    2 ℃

    conditions, carried out at least 4 hours.

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