Production of recombinant blood clotting factors in human cell lines

Production of recombinant blood clotting factors in human cell lines

  • CN 1,454,257 B
  • Filed: 03/21/2001
  • Issued: 01/16/2013
  • Est. Priority Date: 03/22/2000
  • Status: Active Grant
First Claim
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1. factor VIII muteins, B-structural domain in the described mutain between Arg740 and Glu1649 position is replaced by the joint peptide that is rich in Arg of the sequence of SEQ ID NO:

  • 9, and wherein said Factor IX numbering is corresponding to the ripe wild type factor VIII sequence that shows in SEQ ID NO;

    2.

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