PUFA polyketide synthase systems and uses thereof

PUFA polyketide synthase systems and uses thereof

  • CN 1,535,312 A
  • Filed: 04/16/2002
  • Published: 10/06/2004
  • Est. Priority Date: 04/16/2001
  • Status: Active Application
First Claim
Patent Images

1. isolated nucleic acid molecule, it contains the nucleotide sequence that is selected from down group:

  • A. coding is selected from;

    SEQ ID NO;

    2, SEQ ID NO;

    4, SEQ ID NO;

    6, or the nucleotide sequence of the aminoacid sequence of its biological active fragment;

    B. coding is selected from SEQ ID NO;

    8, SEQ ID NO;

    10, SEQ ID NO;

    13, SEQ IDNO;

    18, SEQ ID NO;

    20, SEQ ID NO;

    22, SEQ ID NO;

    24, SEQ ID NO;

    26, SEQ ID NO;

    28, SEQ ID NO;

    30, SEQ I8, SEQ ID NO;

    30, SEQ ID NO;

    32, or the nucleotide sequence of the aminoacid sequence of its biological active fragment;

    C. at least 500 continuous amino acids have nucleotide sequence at least about 60% identical aminoacid sequence in coding and (a) described aminoacid sequence, and wherein said aminoacid sequence has the biologic activity of at least one structural domain of polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) system;

    D. coding and (b) described aminoacid sequence have the nucleotide sequence at least about the aminoacid sequence of 60% homogeny, and wherein said aminoacid sequence has the biologic activity of at least one structural domain of polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) system;

    WithE. with (a), (b), (c), or the complete complementary nucleotide sequence of nucleotide sequence (d).

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