Viral clearance process

Viral clearance process

  • CN 1,576,281 A
  • Filed: 10/14/1998
  • Published: 02/09/2005
  • Est. Priority Date: 10/14/1997
  • Status: Active Grant
First Claim
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1. virus-free anti-D immunoglobulin (Ig) that contains by the preparation of following method, described method comprises:

  • (a) will separate from the anti-D immunoglobulin components that contains of human plasma and mix with the high ionic strength buffers liquid that contains the nonionic vehicle;

    (b) smaller or equal to the supermicro filtration membrane of 30nm mixture is carried out hyperfiltration with the nominal pore size;

    (c) filtered solution of collection hyperfiltration, described filtered solution is the pure substantially virus-free anti-D immunoglobulin (Ig) that contains.

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