Aqueous sustained-release formulations of proteins

Aqueous sustained-release formulations of proteins

  • CN 1,612,752 A
  • Filed: 10/25/2002
  • Published: 05/04/2005
  • Est. Priority Date: 11/07/2001
  • Status: Active Application
First Claim
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1. pharmaceutical preparation comprises:

  • A) a kind of erythropoietin of pharmaceutically active amount;

    B) the acceptable pH buffer agent of a kind of medicine remains between about 6~

    about 9 pH;

    C) a kind of isotonic agent, concentration are about 0~

    about 200 mMs;

    WithD) carboxymethyl ester sodium cellulosate, concentration be total formulation weight about 0.5%~

    about 7%, the molecular weight of described carboxymethyl ester sodium cellulosate is about 50,000 dalton~

    about 1,000,000 dalton.

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