The gene product and uses thereof of differential expression in tumour

The gene product and uses thereof of differential expression in tumour

  • CN 1,646,692 B
  • Filed: 03/12/2003
  • Issued: 12/16/2015
  • Est. Priority Date: 03/13/2002
  • Status: Active Grant
First Claim
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1. detect a test kit for tumor associated antigen TPTE expression or unconventionality expression, described test kit comprises the reagent for following detectionI () detects nucleic acid or its part of the described tumor associated antigen TPTE of coding,(ii) described tumor associated antigen TPTE or its part is detected,(iii) antibody be combined with described tumor associated antigen TPTE or its part is detected, and/or(iv) detection has described tumor associated antigen TPTE or the specific T cell of the mixture between its part and MHC molecule, and described tumor associated antigen TPTE has by the sequence being selected from following encoded by nucleic acid:

  • A () has the nucleic acid of the nucleotide sequence of SEQIDNO;

    19,(b) about the degeneracy nucleic acid of the nucleic acid of (a), andC nucleic acid that () is same with the nucleic acid at least 98% or at least 99% of (a) or (b).

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