Vaccine compositions containing amyloid beta1-6 antigen arrays

Vaccine compositions containing amyloid beta1-6 antigen arrays

  • CN 1,674,934 B
  • Filed: 07/18/2003
  • Issued: 01/02/2013
  • Est. Priority Date: 07/19/2002
  • Status: Active Grant
First Claim
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1. compositions, it comprises:

  • (a) have the core granule of at least one the first attachment site, wherein said core granule is the virus-like particle of RNA phage;

    With(b) at least one has the A β

    1-6 peptide of at least one the second attachment site, and wherein said the second attachment site is selected from;

    (i) non-natural is present in the attachment site on the described A β

    1-6 peptide;

    With(ii) naturally occurring attachment site on the described A β

    1-6 peptide,Wherein said the second attachment site can associate with described the first attachment site;

    And wherein said A β

    1-6 peptide and described core granule interact to form in order and the antigen array that repeats by described association.

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