New process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

New process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

CN
  • CN 1,683,341 A
  • Filed: 02/18/2005
  • Published: 10/19/2005
  • Est. Priority Date: 04/13/2004
  • Status: Active Application
First Claim
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1. , synthesis type (I) S 16257-2 or 3-{3-[{[(7S)-3,4-dimethoxy dicyclo [4.2.0] hot-1,3,5-triolefin-7-yl]-methyl } (methyl) amino] propyl group }-7,8-dimethoxy-1,3,4,5-tetrahydrochysene-2H-3-benzo-aza _-2-ketone, itself and the additive salt of pharmaceutically acceptable acid and the method for hydrate thereof, (I) is as follows for described formula:

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