Multi vitamin oral disintegrating tablet formulation and its preparing method

Multi vitamin oral disintegrating tablet formulation and its preparing method

  • CN 1,775,289 B
  • Filed: 11/15/2004
  • Issued: 08/24/2011
  • Est. Priority Date: 11/15/2004
  • Status: Active Grant
First Claim
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1. multi vitamin oral disintegrating tablet, it is characterized in that:

  • its composition is by weight percentage;

    Multivitamin combination 5~

    30%;

    Filler 20~

    60%, filler are the combination of microcrystalline Cellulose, lactose and mannitol, the combination of the combination of microcrystalline Cellulose, lactose, xylitol and dextrin or microcrystalline Cellulose, lactose, mannitol and dextrin;

    Disintegrating agent 10~

    40%, disintegrating agent are the combination of crospolyvinylpyrrolidone or crospolyvinylpyrrolidone and low-substituted hydroxypropyl methylcellulose;

    Effervescent 0~

    32%, the effervescent acid-base pair that to be citric acid, tartaric acid or malic acid form with sodium bicarbonate or sodium carbonate;

    Correctives 1~

    10%, correctives are mannitol, essence and A Siba one or more the combination in sweet;

    Binding agent 0.4~

    10%, binding agent are one or more the combination in hydroxypropyl emthylcellulose, polyvinylpyrrolidone, pregelatinized Starch, polyacrylic resin, arabic gum and the pectin;

    Lubricant 0.05~

    5%, lubricant are a kind of in magnesium stearate, polyethylene glycol 6000, Pulvis Talci, Stepanol MG and the micropowder silica gel;

    More than various composition sums be 100%.

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