Substituted aromatic radical biguanide compounds and the application of their medicine composition in preparing medicine for resisting malignant tumors

Substituted aromatic radical biguanide compounds and the application of their medicine composition in preparing medicine for resisting malignant tumors

  • CN 1,846,694 B
  • Filed: 04/12/2005
  • Issued: 02/01/2012
  • Est. Priority Date: 04/12/2005
  • Status: Active Grant
First Claim
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1. the application of substituted aromatic base biguanide compound aspect preparation inhibition tumor invasion diversion medicaments;

  • It is selected from the following chemical compound one or more;

    N-benzyl biguanide p-methyl benzenesulfonic acid salt;

    N-{4-[(trifluoromethyl) sulfo-] phenyl } biguanide hydrochloride;

    N-(3-chloro-phenoxy group) biguanide;

    3-biguanide-ethyl benzoate hydrochlorate;

    N-(2-ethylphenyl) biguanide hydrochloride;

    N-benzyl-N-phenyl biguanide p-methyl benzenesulfonic acid salt;

    N-(3, the 4-Dichlorobenzene base) biguanide;

    N-{3-[(methyl) sulfo-] phenyl } biguanide hydrochloride;

    N-{2-[(methyl) sulfo-] phenyl } biguanide hydrochloride;

    N-(2-chloro-5-trifluoromethyl) biguanide;

    N-(2-ethoxyl phenenyl) biguanide;

    N-(5-chloro-2-aminomethyl phenyl) biguanide;

    N-{4-[(difluoromethyl) sulfo-] phenyl } biguanide hydrochloride;

    N-(3-chloro-4-ethoxy benzyl) biguanide hydrochloride;

    N-(3-chloro-4-methoxy-benzyl) biguanide hydrochloride;

    N-(4-chloro-2-aminomethyl phenyl) biguanide hydrochloride;

    N-(3-chloro-4-fluorophenyl) biguanide hydrochloride;

    N-(4-Trifluoromethoxyphen-l) biguanide hydrochloride;

    N-(3-nitrobenzophenone) biguanide;

    N-(3-chloro-4-fluorobenzene methoxyl group) biguanide;

    N-(2, the 4-Dichlorobenzene base) biguanide hydrochloride;

    N-(2, the 3-Dichlorobenzene base) biguanide hydrochloride;

    N-(4-fluorophenyl) biguanide hydrochloride.

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